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Despite numerous efforts, the accurate determination of trace biomolecules with zeptomolar sensitivity remains elusive. Here, a 3D carbon nanomaze (CAM) electrode for the ultrasensitive detection of trace biomolecules such as nucleic acids, proteins, and extracellular vesicles is reported. The CAM electrode consists of an interlaced carbon fiber array on which intercrossed graphene sheets are vertically...
In article number 2006521, Danqun Huo, Yang Luo, Changjun Hou, and co‐workers present a universal 3D carbon nanomaze (CAM) biosensing platform by integrating a programmable 3D DNAT‐ structured probe and in situ grown graphene sheets for the zeptomolar level detection of cancer biomarkers with a lowest LOD of 23 zM. Through simple functionalization by appending various biomolecular probes of interest,...
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