2D conductive metal–organic frameworks (2D c‐MOFs) as emerging 2D graphene‐like crystalline materials have become a promising platform for energy storage. However, their capacity is largely constrained by the limited number of electroactive sites. Integrating multiple redox‐active moieties into the 2D c‐MOF skeletons is an efficient strategy toward high‐performance battery cathodes. Herein, by tailoring an anthraquinone‐based multitopic catechol ligand, a novel quinone‐containing copper‐catecholate MOF (Cu‐TBPQ MOF) is successfully developed. The Cu‐TBPQ MOF exhibits abundant porosity, excellent conductivity, and multiple redox‐active sites. These characteristics make it an ideal candidate as a cathode material for zinc ion batteries. Notably, the Cu‐TBPQ MOF demonstrates an impressive reversible specific capacity of 371.2 mAh g−1 at a current density of 50 mA g−1. Furthermore, it exhibits outstanding rate capability and long‐term durability, retaining a capacity of 120.3 mAh g−1 at a high current density of 2.0 A g−1 even after 500 charge–discharge cycles. The successful enrichment of redox‐active sites in the work opens up new avenues for the rational design of electrochemically active 2D c‐MOFs, enhancing their potential for advanced energy storage applications.