The concept of selective denervation around the knee joint has received increasing attention and recognition as a legitimate treatment modality forintractable knee pain due to neuromata. Our ability to surgically manage these patients has been enhanced as our understanding of the innervation of the human knee joint has improved. Much of this is due to the pioneering work of one of my long-standing mentors, A. Lee Dellon, MD. His anatomic studies detailing the neural pathways have facilitated our understanding of the sensory mechanisms responsible for pain around the knee joint.