A seizure that persists for a sufficient length of time or is repeated frequently enough to produce a fixed and enduring epileptic condition Distinct seizure phenomenon – not simply a prolonged seizure; status epilepticus (SE) represents a reconfiguration of excitatory and inhibitory networks within the brain Historically, experts in the field arbitrarily defined SE as unremitting seizures for a specific duration of 30 min Subsequently, shorter seizure epochs have been defined as SE Based on typical seizure duration of 1–2 min, SE should likely be considered in seizure events that are 5–10 min in duration; this definition of SE with a shortened epoch of onset is supported by the American Academy of Neurology, the American Epilepsy Society, and the International League Against Epilepsy (ILAE)