This article serves as an introduction to this special issue of Journal of Adult Development that deals with the topic of aging and autobiographical memory. Methodological issues, empirical findings, and theoretical frameworks that bear on older adults' autobiographical recall are discussed. Special emphasis is placed on an examination of the factors that underlie the offset of infantile amnesia and the reminiscence bump. An integrative approach to the study of aging and autobiographical memory is proposed that brings together paradigms from experimental psychology, clinical neuropsychology, and neuroimaging.