As an emerging interdisciplinary field, oncofertility bridges oncology, reproductive endocrinology, and infertility with the goal of expanding reproductive options for women with cancer. Oncofertility is currently gaining significant attention from professionals in many related fields and is undergoing considerable scrutiny in part because of the many compelling ethical dilemmas it raises. To illustrate some of the dilemmas providers face, and make suggestions for clinical care, this chapter presents three clinical scenarios encountered in medical practice. An increased awareness of the complex problems involved should help prepare clinicians for some of the challenges posed by this rapidly expanding discipline.