Feedback concerning facts about oncological patient care is one part of a targeted communication process, which involves information and statements as well as possible reactions and subsequent consequences. At least four aspects are involved in a feedback response: the recipient, the content, a date and the reaction of the recipient. The list of persons potentially interested in the response is long and includes among others, patients and their relatives, physicians and hospitals, health insurance companies and health politicians. For physicians and hospitals, interesting aspects and facts are for example, statements about data quality, description of the course of disease, implementation of guidelines, benchmarking, facts for third party certification until incentives for innovation and research. Regional clinical cancer registries are able to offer an infrastructure for feedback and benchmarking, which can provide important support for targeted communication processes. Such support facilitates optimal health care and improves transparency in quality of care in oncology. Each clinical cancer registry should feel obliged to support such communication processes.