It is believed that for complex workpieces and small lot sizes complete machining with multi-technology platforms reduces cycle times compared to multiple stand-alone machines and is economically more efficient. However, so far in literature no mathematical model has been applied to compare these alternatives with respect to cost and productivity. This paper introduces a mathematical model for part costs and productivity and examines conditions under which multi-technology platforms are economically efficient. It is concluded that depending on the reduction of reconfiguration and processing times efficient production with multi-technology platforms is not solely limited to small lot sizes.