In the present study, the effect of loading type on S-N fatigue behavior was examined using a 0.7 mm thick SPRC340 (Fe-0.08C-0.7Mn-0.5Si-0.12P-0.03S) steel sheet product. In contrast with the commonly held belief that the apparent fatigue resistance under bending is higher than that under uniaxial loading, the present specimens tended to show lower fatigue resistance under bending than under uniaxial loading. This trend appeared to be associated with several factors, including multi-site crack initiation on both sides of the specimen in bending, increasing error in the elastic bending stress calculation, and cyclic hardening during fatigue. The effects of loading type, including uniaxial loading and bending, on the S-N fatigue behavior are discussed.