We have been witnessing numerous world crises and disasters—from ecological to military to economic, with global dynamics likely to be increasing further. The paper highlights known holistic and gestalt principles mainly used for a single brain, extending them to any distributed systems which may need high integrity and performance in reaction to unpredictable situations. A higher organizational layer is proposed enabling any distributed resources to behave as an organism having global “consciousness” and pursuing global goals. This “over-operability” layer is established by implanting into key system points the same copy of a universal intelligent module, which can communicate with other such modules and interpret collectively global mission scenarios presented in a special Distributed Scenario Language. The behavioral scenarios can be injected from any module, and then self-replicate, self-modify, and self-spread throughout the system to be managed, tasking individual components, activating distributed resources, and establishing runtime infrastructures supporting system’s integrity. Existing and prospective applications are outlined and discussed, confirming the paradigm’s suitability for solving world problems.