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The recognition of the flame propagation is a significant issue for the safety and protections in various industrial plants. In this research, computational fluid dynamic is applied to simulate the flow features and flame deflagration inside a confined chamber with obstacles. This study has focused on the transient progress of flame to determine the main effective parameters affecting flow feature and flame propagation. In order to simulate the limited obstacle channel, a three-dimensional model is developed using large eddy simulation (LES) technique. The effects of the obstacle geometry on the flame propagation are comprehensively investigated. Moreover, the influence of various gases (acetylene, hydrogen, methane, propane and butane) on the deflagration progress is thoroughly studied to recognize the main characteristics of the flame structure. Our results show that the flame propagation significantly decreases as the shape of the obstacle becomes similar to a sphere. Our findings also demonstrate that the peak pressure of the flame rises considerably when gases with high multiplying of density and laminar burning velocity (such as acetylene) are blasted inside a limited channel. Quantitative assessment showed that the explosion overpressure has inverse relation with the sphericity coefficient by the power of 2.07 and direct relation with the fuel type through an exponential function.