The decay of the B + meson to the D + and K 0* mesons is a pure annihilation decay. For this reason, in the framework of the quantum chromodynamics factorization (QCDF) approach, this decay has a small amplitude and a small branching ratio. In this research we find that, before the D + and K 0* mesons are produced in the final states, pair mesons such as D s +* and D s +ρ0 are produced. The intermediate-state mesons via the exchange of K 0(K 0*) and D +(D +*) go to the D + and K 0* final state mesons. However we calculate the B + → D + K 0* decay in two different frameworks. The first framework is the QCDF method and the second one is final state interaction (FSI). The experimental branching ratio of B + → D + K 0* decay is less than 3 × 10–6, and our results obtained by the QCDF method and FSI are (0.35 ± 0.04) × 10–6 and (2.94 ± 0.10) × 10–6, respectively.