The paranasal sinuses, the nose, mouth and nasopharynx as well as the corresponding lymphatic area are of very special importance due to their exposed topography and in regard to their immunologic protective function. For a solid therapy, the correct assignment of the different terms to the functional circuits is essential. Attention must be given to their energetic interrelations. Great value has to be set on the different allocation of sense organs, the areas of mucous membrane, odontones, sinuses and lymphatic areas. The consideration of the reference between the functional circuits and the illness and attention to the energetic relation are of eminent importance for regulatory therapy. Because of many complex connections and dependences, all diseases of the oronasal and oropharyngeal area have to be evaluated in a holistic sense according to TCM and coordination of interdisciplinary treatment.