Environmental tobacco smoke is an important factor in indoor air quality and public health. In this study, the impacts of cigarette smoking on the characteristics of PM10, PM2.5, and PM1 and their corresponding toxic metals in 50 indoor environments before and after smoking from 10 popular cigarette brands sold in Kuwait were investigated. Misleading advertisement branded ‘medium strong’ with less nicotine volume instigates the smokers use more cigarettes that may cause human health effects. Results showed high PM10 level (range 150–1100 µg m−3) followed by PM2.5 (range 100–880 µg m−3) and PM1 (range 52–530 µg m−3) after smoking. Establishment-wise, highest levels of particulate regardless the sizes were found in storehouse and lowest were observed in offices. The mean PM2.5/PM10 and PM1/PM2.5 ratios were in the range of 0.73–0.86 and 0.66–0.80, respectively, after smoking demonstrating that indoor PM10 was mostly composed of fine particles, which confirms that cigarette smoke had a dominate impact on the presence of smaller particles. Toxic metals level exhibited similar patterns as those observed in particulate in the sequence of Pb > Cd > Sb > Ba > Hg. This study recommends the preventive measures and suggests policy makers to take stringent measures against cigarette smoking in Kuwait to protect public health.