Over the years, injection molding has been a premier manufacturing technique in the production of intricate polymer components. Its molding efficiency rests on the shoulders of multiple process and machine parameters, which dictate the final product quality in terms of multiple output responses. It is imperative to state that a precise optimization of various input parameters is paramount for achieving the desired quality indices. In this article, a review of different techniques employed till date for optimizing various injection molding parameters is presented along with their advantages and limitations. It is found in the review that a complete intelligent technique operable without human interference is yet to be developed.