The study area comprises the southeastern part of the Western Desert of Egypt. The aims of the present study are to delineate the major surface and subsurface structures and to evaluate tectonic framework of the study area. Surface studies of the present work are based mainly on data from two different types of remote sensing systems: 15 cloud-free Landsat Enhanced Thematic Mapper Plus (ETM+) images and Shuttle Radar Topography Mission (SRTM) DEM data. The remote sensing data were used to recognize and extract geological lineaments by calculating and interpreting DEM derivatives, including shaded relief maps, slope maps, and traverse profiles. A Bouguer anomaly map (scale 1:500,000) was used to delineate a detailed picture of the subsurface structure in the study area. The analysis of surface data, including SRTM DEM and ETM+, was combined with subsurface data, including Bouguer anomaly map, and gave new insight into the tectonic and structure patterns of the study area.