A multiple factor analysis is developed to assess the differences in the economic performance and employment levels of social cooperatives in three main geographical areas: North, Central and South Italy, between 2008 and 2011. The results showed that despite the global economic and financial meltdown, the social cooperatives in these areas increased their overall turnover and total assets between 2008 and 2011. Furthermore, the employment data showed a positive trend during this period. The analysis also found that the prolonged crisis in 2010 and 2011 affected mainly the southern regions, where conjunctural factors exacerbated long-term structural deficiencies.