Coupled resonator optical waveguide (CROW) structures were investigated as a whispering gallery mode optical resonator for biosensing applications. A single mode optical fiber taper was used to evanescently couple light into the microspheres. We have simulated the theoretical model of the crow structure with two and three microspheres. The coupled-resonator-induced transparency (CRIT) phenomenon was observed in the crow structures. In this paper, two crow structures and a single microsphere resonator are compared with each other. We have reported the high sensitivity of the crow structures compared to a single microsphere. We have demonstrated apparent shifts of CRIT transparent peak when the virus nanoparticles are placed on the surface of the microsphere. As a result, these crow structures can be used as a biosensing sensor with high sensitivity. The theoretical simulation was carried out at the operating wavelength of 1550 nm.