Objective. To evaluate the use of different treatment systems to increase the efficacy of the rehabilitation of patients with neglect syndrome (NS) after stroke. Materials and methods. The effects of observing a protocol for managing patients with NS and using Ceraxon (citicoline) on the extent of recovery of neurological functions, the level of daily adaptation, and elimination of NS were studied in stroke patients. Treatment results from 120 patients were analyzed. The extent of restoration of functions was assessed using the Lindmark scale, the level of daily adaptation using the Barthel scale and the Merton and Sutton scale, the state of cognitive functions using the MMSE and the Frontal Assessment Battery, and psychoemotional status using the Beck questionnaire. Treatment efficacy was also evaluated in terms of the absence of the characteristic signs of NS. Results and conclusion. These studies showed that complex rehabilitation following the protocol for managing patients with NS and Ceraxon significantly increased rehabilitation efficacy in this group of patients.