Mosquito vector control is a crucial challenge nowadays. Recently, the relevance of screening poorly studied plant products for green synthesis of nanopesticides was highlighted. Different plant products for nanosynthesis led to nano-composites with distinct biophysical features and toxicity. Here we fabricated silver nanoparticles capped with metabolites from Fumaria indica aqueous extract. Several biophysical methods were used to validate nanosynthesis F. indica-synthesized nanomaterial showed high efficacy as pesticide on Anopheles subpictus (LC50 = 10.34 µg/ml), Aedes albopictus (LC50 = 11.42 µg/ml) and Culex tritaeniorhynchus (LC50 = 12.50 µg/ml) larvae, allowing us to propose this easy to obtain nano-material as an effective source of novel mosquito pesticides.