Realistic rendering of natural scenes captured by digital cameras is the ultimate goal of image processing. In recent years, high dynamic range (HDR) imaging has received increasing attention for producing high-quality images. Multi-exposure image fusion is one of the most popular methods to achieve an HDR-like image without tone mapping. However, existing fusion methods may result in serious color distortions due to the inappropriate image attribute selection. In this paper, we propose a multi-exposure image fusion method based on human visual perception with overall image quality index (OIQ) and local saturation. We adopt OIQ and local saturation to enhance the fusion quality of multi-exposure images and achieve natural color reproduction. Experimental results show that the proposed method can successfully enhance image quality and achieve realistic rendering of natural scenes.