Development of embedded automotive systems has become tremendously complex in recent years. The trend of replacing traditional mechanical systems by modern embedded systems, and the launch of automotive multi-core systems enable deployment of more advanced control strategies. However, these applications require different safety concepts with different levels of criticality; and providing consistency of the safety concept during the entire product lifecycle is a tedious task. Additionally, new automotive safety standards, such as ISO 26262, and the de-facto industry standard AUTOSAR require efficient and consistent product development and tool support. The aim of the presented work is to establish a model-driven system and safety-engineering framework to support the seamless description of safety-critical systems, from requirements at the system level to final component implementation.