This paper presents an innovative approach for the study of the adhesion of dust particles on the surface of CSP reflector mirrors. Three types of CSP mirrors are studied, the first one is the commercial mirror used at NOOR 1 project, the second one is a CSP mirror with hydrophobic amorphous Al2O3 nano-coating and the third one is CSP mirror with hydrophilic TiO2 nano-coating. The dust particles were collected from three potential regions for CSP plant installation in Morocco (Ouarzazate, Tinghir and Midelt regions). Based on the extended DLVO theory and the Good–van Oss model, the energy of adhesion was determined between the different types of mirrors and the sand samples. The results showed that the work of adhesion between CSP mirrors with hydrophobic alumina nano-coating and Tinghir dust particles has the minimum value of 42.78 mJ/m2 compared to other samples. This result can be explained by the hydrophobic nature of the surface of this mirror and the nature of the clay minerals in the soil extracted from the Tinghir site. The results of X-ray diffraction showed that the kaolinite type of clay minerals is present in major quantities in Tinghir and this explains the low adhesiveness of Tinghir dust on the surface of the mirrors, since kaolinite is characterized by its very low water absorption and hence very low adhesion to a solid surface.