In this paper, we prove the incompressible limit of all-time strong solutions to the three-dimensional full compressible Navier–Stokes equations. Here the velocity field and temperature satisfy the Dirichlet boundary condition and convective boundary condition, respectively. The uniform estimates in both the Mach number $${\epsilon\in(0,\overline{\epsilon}]}$$ ϵ ∈ ( 0 , ϵ ¯ ] and time $${t\in[0,\infty)}$$ t ∈ [ 0 , ∞ ) are established by deriving a differential inequality with decay property, where $${\overline{\epsilon} \in(0,1]}$$ ϵ ¯ ∈ ( 0 , 1 ] is a constant. Based on these uniform estimates, the global solution of full compressible Navier–Stokes equations with “well-prepared” initial conditions converges to the one of isentropic incompressible Navier–Stokes equations as the Mach number goes to zero.