Sugarcane somaclones regenerated though leaf callus cultures of variety CoS 91279 showed wide variations for red rot resistance against four isolates ofColletotrichum falcatum Went. Out of 42 somaclones tested, only three viz. Soma 16, 27 and 37 were found moderately resistant by plug method of inoculation. Rest of the somaclones showed varying degrees of susceptibility. Most of the somaclones, though regenerated from toxin resistant calli, were found moderately to highly susceptible against the test pathogen. Two somacolnes viz. Soma 37 and 27 were found resistant by nodal method of inoculation.