Our studies were focused on heavy metals (Cd, Cu, Zn, and Pb) and pesticides analysis from two different types of marine algae in order to assess their capabilities to be used as raw material for pharmaceutical purposes without risks for human health. The analysed algae, Cystoseira barbata and Ceramium rubrum, have been collected from Romanian Black Sea Coast in the southern zone Tuzla — Vama Veche where the biomass has increased in 2007. The used analytical techniques were atomic absorption spectrometry (AAS) for heavy metals and gas chromatography with electron capture detector (GC-ECD) and thermoionic specific detector (GC-TSD) for organochlorine respectively organo-phosphoric pesticides. The results indicate that heavy metals and pesticides levels are very low, similar with other reported data. The bioaccumulation abilities for studied contaminants are higher for Ceramium rubrum than for Cystoseira barbata.