Cross-sector partnerships are essential to enter market segments at the “Base of the Pyramid” (BoP). Co-creation of innovative products, services, and inclusive business model are desired outcomes of collaboration. However, this is rarely achieved. BoP research still lacks empirical analyses of preconditions and the process of cross sector collaboration. Based on interorganizational learning literature this paper develops a research model for empirical evaluations. Motivation, receptiveness, and transparency are identified as major preconditions of interorganizational learning. Without an interorganizational learning process co-creation of pioneering solutions is unlikely to occur in cross-sector partnerships.