Children with chronic medical conditions are typically included in regular education settings. School mental health clinicians can play a key role in enhancing the social and cognitive development of these children. This manuscript presents a review of literature indicating ways to assist children with medical conditions in schools. Information about assessment, family-centered interventions, and school reintegration programs is reviewed. Additionally, suggestions about how clinicians can assist with school absences, compliance with medical regimens, case management, teacher training, counseling parents, and improving social acceptance of these children are presented. Lobbying for comprehensive educational planning for children with medical conditions is a goal for the future.