Let C be a closed and convex subset of a real Hilbert space H. Let T be a 2-generalized hybrid mapping of C into itself, let A be an α-inverse strongly-monotone mapping of C into H, and let B and F be maximal monotone operators on and respectively. The purpose of this paper is to introduce a general iterative scheme for finding a point of which is a unique solution of a hierarchical variational inequality, where is the set of fixed points of T, and are the sets of zero points of and F, respectively. A strong convergence theorem is established under appropriate conditions imposed on the parameters. Further, we consider the problem for finding a common element of the set of solutions of a mathematical model related to mixed equilibrium problems and the set of fixed points of a 2-generalized hybrid mapping in a real Hilbert space.