The immunolocation of cystationine β-synthase in the motor, sensitive, and autonomic nuclei of the cerebral pons was studied on the material from 8 healthy men aged 18-44 years dead from traumas not involving the CNS. The motor nuclei contained numerous large intensely stained cells, while the sensitive and autonomic nuclei contained many small neurons with low levels of cystationine β-synthase marker. However, cells with intense reaction were found among small neurons. They were located mainly at the nuclear periphery, between the nuclei or between the nuclei and conduction tracts. The content of immunopositive neurons in the studied nuclei varied from 2 to 14%. The level of these cells in motor nuclei was 3-4-fold higher than in sensitive and autonomic nuclei.