Cigarette smoking continues to be the single largest preventable cause of premature death in the United States. Unfortunately, smoking cessation rates in the United States have stalled despite the availability of effective smoking cessation treatments. Although community-based smoking cessation services delivered in person, via the phone, and via the Internet have been shown to be effective channels of intervention, few smokers actually use the services for smoking cessation treatment. Recent studies suggest that pursuing innovative strategies may lead to increased reach and a potential increase in cessation rates. As such, researchers and clinicians can take advantage of these strategies and programs to help promote smoking cessation resources that can be used to effectively treat nicotine dependence and ultimately reduce cardiovascular disease and cancer.