In this paper, a brief discussion on microfluidic devices and micromixer were made to clarify the difficult issues and category thus encountered. Based on Taylor dispersion mechanism, a new kind of micromixing pattern was investigated. Theoretical hydrodynamics model was established to characterize the Taylor dispersion behavior of the micro fluid. Numerical simulation and parametric evaluation were performed on the micromixing pattern enabled by the time-interleaved segmentation feeding of fluid. And good mixing efficiency was obtained. The present research is expected to be of important reference for better understanding the Taylor micromixing process. The corresponding method thus developed can serve as a useful tool for designing future micromixer.