After a brief biography of Jaap van Brakel we set out his appropriation and use of the distinction between the manifest image and the scientific image of the world. In a certain sense van Brakel gives priority to the manifest image as the ultimate source of meaning in chemical discourses. He does not take sides in the debate about nominal and real essences, twin earths and so, but presents a compromise. As an active practitioner of the chemical arts he emphasises the indispensability of models as a main tool for chemical thinking. We then turn to van Brakel’s interest in forging an intercultural point of view in which philosophy of chemistry plays an important part.