Titanium alloys have been successfully applied for aerospace, ship, and chemical industries because they possess many good characteristics such as high strength to weight ratio, superior corrosion resistance, and excellent high temperature resistance. Though these alloys show reasonable weldability characteristics, the joint properties are greatly influenced by the welding processes. The evaluation and prediction of fatigue life are very important for the welded joints to avoid catastrophic failure particularly in titanium alloys. This article compares the fatigue performance of Ti-6Al-4V alloy fabricated by gas tungsten arc welding, laser beam welding, and electron beam welding processes. The resultant fatigue properties of the welded joints are correlated with the tensile properties and microstructural characteristics. Of the three processes considered the joint welded by laser beam welding exhibits higher fatigue limit when compared with the other two processes due to the presence of fine lamellar microstructure in the weld metal region.