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Imaging plays an Important role In the multidisciplinary study of both primary and metastatic gastrointestinal stromal tumors (GISTs), thanks to the numerous radiologic techniques, such as conventional radiography, ultrasonography with and without color Doppler, contrast-enhanced ultrasound (CEUS), CT, MR and CT/PET, as well as endoscopic techniques such as endoscopy and endoscopic ultrasound (EUS).
Conventional radiography Is nowadays seldom Indicated for the diagnosis and follow-up of patients with GISTs. Abdominal plain films, single and double-contrast barium studies of the gastrointestinal tract may, however, be useful (In occasional cases) In demonstrating direct and/or Indirect signs of GISTs. The radiological characteristics of this kind of tumor on conventional barium studies...
Gastrointestinal stromal tumors (GISTs) are rare tumors, that are usually discovered incidentally during endoscopy. Occasionally, however, they are symptomatic and present mainly with gastrointestinal bleeding. Since GISTs often present as submucosal lesions, covered by intact and normal mucosa, they cannot be differentiated from other submucosal lesions at traditional endoscopy. This technique...
Transabdominal ultrasound (US) Is employed In the screening, detection, differential diagnosis, staging, and follow-up of gastrointestinal stromal tumors (GISTs). Although there are well-known limitations in the use of ultrasounds to scan the gastrointestinal tract, US can assess the primary site of growth of GISTs as well as their metastasis to the liven Gray-scale US, color-power-Doppler techniques,...
CT is considered to be the imaging modality of choice for the detection, staging, surgical planning and follow-up of patients with GIST. We describe CT features of GISTs. They commonly have an exophytic growth pattern and appear as large masses outside the organ of origin. Intramural and intraluminal masses are less common radiologic manifestations. GISTs may contain areas of hemorrhage, necrosis,...
Diagnostic imaging provides a valuable contribution to the study of primary and metastatic gastrointestinal stromal tumors (GISTs) with Magnetic Resonance (MR). MR can be used In the Identification, characterization and staging of GISTs, as well as In the evaluation of response to treatment, showing the tissue changes Induced In cancer cells by molecular targeted therapies, Including myxohyaline changes,...
Today, PET/CT is an essential diagnostic tool in the clinical assessment of GIST, mainly during follow-up. PET/CT is sensitive in the early detection of the pharmacological response to Imatinib Mesylate and it is specific in the follow-up of metastatic disease. In 2004, Choi demonstrated that the information deriving from Multidetector CT (MDCT) and PET are complementary in the evaluation of...
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