Apoptosis, also known as programmed cell death, is essential for the regulation of development, the generation of the immune system, and is a central mechanism for maintenance of cellular homeostasis in eukaryotes. This phenomenon of cellular death was described for almost a century, and was named apoptosis only recently to differentiate naturally occurring cell death during development from the acute injury associated necrotic cell death [1]. The apoptosis processes function to maintain equilibrium between cell proliferation and death, while dysregulated apoptosis is involved in development and etiology of many pathological disorders. The acute pathological conditions such as stroke, heart attack, or liver failure as well as chronic neurodegenerative disorders are associated with increased apoptosis resulting in sudden or progressive death of the target tissues. The pathologies of auto-immune disorders and carcinogenesis, on the other hand, arise due in part to the loss or reduced rate of apoptosis.