In order to develop a fatigue design method for actual railroad car and commercial vehicle body structures using the fatigue data of simulated single spot-welded lap joints, we first analyzed the stress distribution and evaluated fatigue strength of spot-welded T-type members that are the components of actual railroad car and commercial vehicle body structures. Next, fatigue design approach of these members using the fatigue data of single spot-welded lap joints was investigated. From our results, we found that, even though there was a quantitative difference of fatigue strength between the single spot-welded joint and the actual members over the same number of fatigue cycles, through the use of appropriate correction, the fatigue design criterion of actual spot-welded members, such as those used in railroad car and commercial vehicle body, can be predicted using the fatigue strength of single spot-welded joint.