Lattice preferred orientations (LPO) of plagioclase and augite are measured on layered gabbro from the Panxi region, Sichuan Province. The LPO concentration [010] of plagioclase and [100] of augite are perpendicular to the foliation, which indicates a kind of growth fabric associated with crystallizing habits of minerals when the magma is solidifying under the compaction. Calculated seismic velocities based on LPO data of minerals give rise to rather strong anisotropy 5.81% and 5.54% for compressional seismic wave (V p) and shear seismic wave (V s), respectively. The experiments at high temperature and high pressure show that the P-wave velocity of layered gabbro is 6.44–6.97 km/s with the maximum V p anisotropy 5.22% and the Poisson’ s ratio is between 0.28–0.31. According to the comparison of fabrics with seismic velocities of layered gabbro, it is suggested that the large-scale layered intrusive body or the similar layered geological body may exist in the lower crust of this area. Such a layered intrusive body which has strong seismic anisotropy may be the seismic reflector in the lower crust.