This chapter aims at presenting the experimental analyses carried out to evaluate the benefits coming from applying the manufacturing system design framework presented in the previous chapters. To this purpose three families of products belonging to different production contexts have been studied. These products have been used as input data of the testing experiments which were aimed at studying the performance of an FFMS when facing production problems characterized by technological and demand evolution. The testing experiments have been carried out by exploiting the software tools that have been developed by implementing the methodologies presented in the previous chapters.