The influence of selected pregelatinized starches on staling of pound cake has been investigated considering wheat and maize pregelatinized starches as flour substitutes. Two baking systems were considered to assess staling: a miniaturized baking system providing degassed baked batter and a conventional oven providing real products. Texture profile analysis, compression, and rupture tests were used to follow texture evolution during storage. Results confirmed the positive effect of partial substitution by pregelatinized starches in microcakes on retarding staling, while the denser structure of pregelatinized starch cakes prevented the same positive impact on texture and staling.