This review describes the characteristics and hot spots of wetland research, including biodiversity protection of wetland, management and restoration of wetland, function and process of wetland, and the theories, methods and scales of landscape ecology. Moreover, some deficits of landscape ecology theory and method were discussed, and the application of landscape ecology to research on wetlands was reviewed specially, involving in the application of landscape structure principle, landscape pattern, and scale and hierarchy theory. In conclusion, landscape ecology plays an enlightening and guiding function on the comprehensive research of wetlands at multi-scales.