The article considers the efficacy of the courses of xenon-oxygen inhalation for the correction of the functional state of aircraft-carrier aviation pilots in a distant sea campaign. The course of inhalation procedures was shown to stabilize the vagosympathetic balance of the body, to restore the level of the functional state of the cardiovascular system, and to retain its functional reserve at an adequate level, thus considerably improving the subjective psychoemotional state of the pilots, which manifests itself in the improvement of self-esteem, an increase in activity, well-being, and mood, as well as in an adequate decrease in the level of reactive anxiety. The results obtained give evidence of the benefits of the use of special xenon-based gas mixtures for correcting the pilots’ functional state in the most stressful periods of their professional activity. Recommendations on the application of this method by military medicine have been given.