Over the course of development, children with autism spectrum disorders (ASDs) may present with an array of behavioral symptoms in addition to the primary impairments in language, socialization, and repetitive/restricted interests. These developmental challenges allow outpatient psychotherapists the opportunity to provide helpful clinical services to children and adolescents with ASDs. This can be best accomplished by combining behavioral strategies that are typically effective with children with ASDs with evidence-based approaches helpful for other psychiatric conditions. Four case examples are provided that review how to use both ASDs and general child clinical interventions with children with ASDs and their families.