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We present two cases of primary splenic malignant lymphoma associated with chronic hepatitis C virus infection detected early by routine follow-up imaging studies. Septumlike structures were seen on postcontrast computed tomography or magnetic resonance imaging, which presented characteristic gross findings. These findings may suggest primary splenic malignant lymphoma during the course of chronic hepatitis C.
Departments of Nuclear Medicine and Diagnostic Imaging, Graduate School of Medicine, Kyoto University,54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan