Speed of sound data, u ijk , of 1,3-dioxolane or 1,4-dioxane(i) + water(j) + propan-1-ol or propan-2-ol(k) ternary mixtures and their sub-binary mixtures, u ij , of 1,3-dioxolane or 1,4-dioxane(i) + water or propan-1-ol or propan-2-ol(j) and water(i) + propan-1-ol or propan-2-ol(j) mixtures have been measured over the entire composition range at 308.15 K. Isentropic compressibility changes of mixing, (κ s E) ij and (κ s E) ijk , for the binary and ternary mixtures have been determined by employing the observed speeds of sound data and densities (calculated from their molar excess volumes data). The (κ s E) ij and (κ s E) ijk values have also been predicated by the graph theoretical approach and the Flory theory. It has been observed that (κ s E) ij and (κ s E) ijk predicted by the graph theoretical approach compare well with their corresponding experimental values.