Purpose: To report ocular perforation that occurred duringretrobulbar injection in 7 highly myopic eyes.Methods: Seven patients with a diagnosis of globe injuryduring retrobulbar injection for ocular anesthesia beforecataract surgery were managed by vitreoretinal surgery. Allinjections were performed by ophthalmologists. The surgeonrecognized the perforation in 4 cases at the time of injection.The preoperative vision was hand motion perception in 4 eyes andlight perception in 3 eyes. All patients underwent vitreoretinalsurgery because of the presence of vitreous hemorrhage and/orretinal detachment diagnosed by funduscopy or ultrasonography. Atthe time of surgery, all eyes had vitreous hemorrhage and 4 eyeshad rhegmatogenous retinal detachment. The number ofvitreoretinal procedures performed was: 1 procedure in 4patients, 2 procedures in 2 patients, and 3 procedures in 1patient. The period of follow-up ranged from 4 months to 4 years,averaging 20 months.Results: At the end of the follow-up period, the retinawas attached in 6 patients. The postoperative vision was 20/400in 3 eyes, finger counting in 3 eyes, and light perception in 1eye.Conclusion: Special care should be taken in retrobulbarinjection of highly myopic globes, which have an increased riskof perforation. The functional outcome of surgical repair ofthese eyes was poor.