Sporotrichosis is a fungal infection of man and animals caused by Sporothrix complex. It usually presents as a lymphocutaneous form, but disseminated disease may occur. Given the paucity of data about HIV/AIDS and sporotrichosis co-infection, a systematic review of reported cases of HIV-associated sporotrichosis found via Pubmed (1984–2013) was done. A total of 39 papers were included, and 58 patients’ data analyzed. Thirty-three (56.9 %) cases were from Brazil and 18 (31 %) from the USA. Patients’ mean age was 37.8 ± 10.4 years; males predominated (84.5 %). The median CD4+ cell count was 97 cells/mm3. The most common clinical forms were disseminated and disseminated cutaneous with 33 (56.9 %) and 10 (17.5 %) patients, respectively. There was a correlation between CD4+ count and clinical categories (p = 0.002). Mortality was 30 % and there was a correlation between central nervous system involvement and death (p < 0.001).