Problems related to social skills deficits and excesses in children are evinced in a myriad of psychopathology. Maneuvering through social interactions is one of the most complex tasks that all human beings do. Social skills involve many psychological systems, such as perception, language, and problem solving. These systems develop throughout childhood and result from biological and environmental influences. Social situations can be problematic when these systems do not function adequately. For example, a child with a language deficit may have difficulty making sense of verbal social cues and communicating desires and opinions. Impulsive children can often make quick decisions that could result in conflicts with others. This chapter will discuss classic literature regarding the nature of evidence-based interventions, who provides the intervention (e.g., parents, siblings, teachers), how best to promote generalization and maintain treatment efficacy over time. Other critical aspects of social skills treatment, as well as strengths, weaknesses, meta-analytic outcome results, and future directions for treatment, will also be reviewed.