Hot forming is an important forming method for production of small and medium sized single-piece pressure vessel dish ends. Thinning of the blank material with increased degree of forming is quite obvious. Present work shows finite element (FE) analysis of hot forming of single-piece hemispherical dish end (SPHDE) for predicting maximum thinning of blank during forming. Thinning analysis is performed for SPHDE of two different ferrous material grades SA-387 Gr22 and SA-516 as per ASME, Section II, Part A (2004). Percentage thinning results of FE analysis are verified with the practical material thinning data. Based on the thinning analysis, empirical relation for calculation of percentage thinning as a function of different dish ends′ geometry parameters is proposed. Empirically predicted percentage thinning is observed to be in good agreement with practical and FE simulation results. Thinning results obtained based on proposed FE simulation and empirical model can be helpful to design engineer in selecting thickness of developed blank considering thinning allowance for hot forming of SPHDE. Thinning analysis data can be used for optimizing the dish end geometrical parameters for minimum thinning during forming.