With the advent of subsecond rotation combined with prospective electrocardiogram (ECG) triggering or retrospective ECG gating, conventional computed tomography (CT) with spiral capability and superior general image quality has challenged electron beam CT (EBCT) in the domain of cardiac imaging. The introduction of multislice CT scanning with the Siemens SOMATOM Volume Zoom with 4 simultaneously scanned slices, half-second rotation, and 250-ms maximum temporal resolution has recently opened new horizons for cardiac CT imaging. ECG-gated multislice spiral CT represents a leap in image quality of CT angiography (CTA) of the coronary arteries. The fast volume coverage allows scanning the heart with 1-mm slice collimation within a single breath-hold (10 cm in 25–30 s) for high-resolution imaging. Three-dimensional reconstruction with approx 1-mm slice width and submillimeter increment provide data of unique quality for visualization of the coronary arteries and of the arterial/venous grafts utilized for surgical revascularization. This chapter will be focused on the clinical background, the previous CT applications in this setting, and the recent results of multidetector-row CT (MDCT) evaluation of coronary artery bypass grafting (CABG).